Healthcare Professionals​

This is an international website for NERLYNX® dedicated to Healthcare professionals ​​

IMPORTANT: the information on this website is based on the European Summary of Product Characteristics. Prescribing Information and indication may vary per country. You must refer to your country prescribing information. Please be aware we do not take responsibility for accessing such information which may not comply with the regulation or usage in your country.

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I am Healthcare Professional inside the EU and I have read the information above​, the Legal Notice and the Privacy Policy

Non Healthcare Professionals

This is an international website for NERLYNX® dedicated to Healthcare Professionals.

I am not a Healthcare Professional inside the EU.

Risk Management Plan

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NERLYNX® Risk Management Plan

Pierre Fabre is committed to make sure that patients can get the full benefit of their treatment. A Risk Management Plan (RMP) agreed with EMA has been set up in Europe.

Learn more on NERLYNX Risk Management Plan.


Specific educational materials are intended to all treating physicians who are expected to prescribe NERLYNX® and to all patients who are expected to get treated with NERLYNX®. They are developed in local language and approved by each Health Competent Authority, as required in the RMP. Thus, educational materials were designed to increase awareness of diarrhoea-induced incidence and help with its management, to be offered to treating physicians and patients prior to treatment initiation.

You can contact your Pierre Fabre local representative or our medical information to get these educational materials.


In addition, the RMP includes the conduction of post-authorization safety studies (PASS) to observe the incidence of permanent discontinuation due to diarrhoea in the routine clinical practice and to evaluate if the upfront education of healthcare professionals and patients can impact on diarrhoea prevention and management. NERLYFE is a European, prospective, observational, PASS to investigate real-world incidence and management of diarrhoea under NERLYNX® as extended adjuvant treatment.


Nerlyfe logo

Study is active

Prospective observational safety study in adult breast cancer patients treated with neratinib
in extended adjuvant in a real-world setting38


To describe
the incidence of discontinuation due to diarrhoea within the first 3 months of treatment with neratinib.38

To assess
the impact of the information provided in the educational materials according to Risk Management Plan engagement.



EU PAS Register number: EUPAS41584.38
For more information about Nerlyfe, please send an email to:

Nerlyfe study design38

Nerlyfe study design

CNS, central nervous system; DDFS, distant disease-free survival; HCPs, Healthcare Professionals; iDFS, invasive disease-free survival; OS, overall survival; PASS, Post-Authorization Safety Study; PO, orally; QoL, quality of life; SmPC, Summary of Product Characteristics; STIDAT, Systemic Therapy-Induced Diarrhoea Assessment Tool.

Contenu de la pop in (ici, un H3)

A noter que le contenu de la pop in est prise en compte pour le SEO.

Il est donc nécessaire de bien baliser les titres. Nous conseillons d'utiliser un H2 ou un H3 (pas de H1).