Nerlynx (neratinib) | HER2+/HR+ breast cancer targeted therapy

Healthcare Professionals

This is an international website for NERLYNX® dedicated to Healthcare professionals

IMPORTANT: the information on this website is based on the European Summary of Product Characteristics. Prescribing Information and indication may vary per country. You must refer to your country prescribing information. Please be aware we do not take responsibility for accessing such information which may not comply with the regulation or usage in your country.

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This is an international website for NERLYNX® dedicated to Healthcare Professionals.

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NERLYNX is indicated for the extended adjuvant treatment of adult patients with early-stage hormone receptor positive HER2-overexpressed/amplified breast cancer and who completed adjuvant trastuzumab-based therapy less than one year ago.

Extended adjuvant treatment with NERLYNX
reduces the risk of HER2+/HR+ breast cancer recurrence by 51% after 2 years^*†‡

Efficacy

Learn about ExteNET
study design and study results.

Safety

Learn about NERLYNX common adverse events, diarrhoea management and other safety information.

Dosing

Learn about NERLYNX recommended
dose and dose adjustments.

*Recurrence is defined as an invasive disease event or death.
†NERLYNX used as extended adjuvant therapy for 12 months following trastuzumab-based therapy completed less than a year ago.
‡At 2 years, in the HER2+/HR+ population subgroup, iDFS = 95.3% in NERLYNX arm (N=670) versus 90.8% in placebo (N=664).

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Il est donc nécessaire de bien baliser les titres. Nous conseillons d'utiliser un H2 ou un H3 (pas de H1).

▼ This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions.
This medicinal product is subject to risk minimization measures.

References
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This is an international website for NERLYNX®. IMPORTANT: the information on this website is based on the European Summary of Product Characteristics. Prescribing Information and indication may vary per country. You must refer to your country prescribing information. Please be aware we do not take responsibility for accessing such information which may not comply with the regulation or usage in your country.

Last update: 01/2023